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  The anti-protozoal drug pentamidine blocks KIR2.x-mediated inward rectifier current by entering the cytoplasmic pore region of the channel.

de Boer, T. P., Nalos, L., Stary, A., Kok, B., Houtman, M. J. C., Antoons, G., et al. (2010). The anti-protozoal drug pentamidine blocks KIR2.x-mediated inward rectifier current by entering the cytoplasmic pore region of the channel. British Journal of Pharmacology, 159(7), 1532-1541. Retrieved from http://www3.interscience.wiley.com/cgi-bin/fulltext/123301886/PDFSTART.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0012-D617-6 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0027-EEA4-2
Genre: Journal Article

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587760.pdf (Publisher version), 745KB
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 Creators:
de Boer, T. P., Author
Nalos, L., Author
Stary, A.1, Author              
Kok, B., Author
Houtman, M. J. C., Author
Antoons, G., Author
van Feen, T. A. B., Author
Beekman, J. D. M., Author
de Groot, B. L.1, Author              
Opthof, T., Author
Rook, M. B., Author
Vos, M. A., Author
van der Heyden, M. A. G., Author
Affiliations:
1Research Group of Computational Biomolecular Dynamics, MPI for biophysical chemistry, Max Planck Society, ou_578573              

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Free keywords: inward rectifier current; /K1; KIR2.1; pentamidine; ECG; arrhythmia; molecular modelling
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 Dates: 2010-02-24
 Publication Status: Published in print
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Title: British Journal of Pharmacology
Source Genre: Journal
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Pages: - Volume / Issue: 159 (7) Sequence Number: - Start / End Page: 1532 - 1541 Identifier: -