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  Pre-fibrillar α-synuclein variants with impaired bold β-structure increase neurotoxicity in Parkinson's disease models.

Karpinar, P., Gajula Balija, M. B., Kügler, S., Opazo, F., Rezaei-Ghaleh, N., Wender, N., et al. (2009). Pre-fibrillar α-synuclein variants with impaired bold β-structure increase neurotoxicity in Parkinson's disease models. EMBO Journal, 28(20), 3256-3268. doi:10.1038/emboj.2009.257.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0012-D78E-1 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0028-97AE-B
Genre: Journal Article

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 Creators:
Karpinar, P.1, Author              
Gajula Balija, M. B.2, Author              
Kügler, S., Author
Opazo, F., Author
Rezaei-Ghaleh, N.1, Author              
Wender, N., Author
Kim, H. Y.1, Author              
Taschenberger, G., Author
Falkenburger, B. H., Author
Heise, H.3, Author              
Kumar, A.4, Author              
Riedel, D.5, Author              
Fichtner, L., Author
Voigt, A.2, Author              
Braus, G. H., Author
Giller, K.6, Author              
Becker, S.6, Author              
Herzig, A.2, Author              
Baldus, M.3, Author              
Jäckle, H.2, Author              
Eimer, S., AuthorSchulz, J. B., AuthorGriesinger, C.6, Author              Zweckstetter, M.1, Author               more..
Affiliations:
1Research Group of Protein Structure Determination using NMR, MPI for biophysical chemistry, Max Planck Society, ou_578571              
2Department of Molecular Developmental Biology, MPI for biophysical chemistry, Max Planck Society, ou_578590              
3Research Group of Solid State NMR Spectroscopy, MPI for biophysical chemistry, Max Planck Society, ou_persistent22              
4Research Group of Solid-State NMR, MPI for biophysical chemistry, Max Planck Society, ou_persistent35              
5Facility for Electron Microscopy, MPI for biophysical chemistry, Max Planck Society, ou_578615              
6Department of NMR Based Structural Biology, MPI for biophysical chemistry, Max Planck Society, ou_578567              

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Free keywords: neurodegeneration; oligomer; Parkinson's disease; structure; alpha-synuclein
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Language(s): eng - English
 Dates: 2009-09
 Publication Status: Published in print
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 Rev. Method: Peer
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Title: EMBO Journal
Source Genre: Journal
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Pages: - Volume / Issue: 28 (20) Sequence Number: - Start / End Page: 3256 - 3268 Identifier: -