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  Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor.

Rummel, A., Haefner, K., Mahrhold, S., Darashchonak, N., Holt, M., Jahn, R., et al. (2009). Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor. Journal of Neurochemistry, 110(6), 1942-1954. Retrieved from http://www3.interscience.wiley.com/cgi-bin/fulltext/122521718/PDFSTART.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0012-D7DE-F Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0029-0C2A-3
Genre: Journal Article

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588028.pdf (Publisher version), 683KB
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 Creators:
Rummel, A., Author
Haefner, K., Author
Mahrhold, S., Author
Darashchonak, N., Author
Holt, M.1, Author              
Jahn, R.1, Author              
Beermann, S., Author
Karnath, T., Author
Bigalke, H., Author
Binz, T., Author
Affiliations:
1Department of Neurobiology, MPI for biophysical chemistry, Max Planck Society, ou_578595              

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Free keywords: botulinum neurotoxin; ganglioside binding site; ganglioside dependence; protein receptor; stimulated neurotoxin uptake; synaptic vesicle glycoprotein 2; tetanus neurotoxin
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Language(s): eng - English
 Dates: 2009-07-23
 Publication Status: Published in print
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Title: Journal of Neurochemistry
Source Genre: Journal
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Pages: - Volume / Issue: 110 (6) Sequence Number: - Start / End Page: 1942 - 1954 Identifier: -