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  Membrane fusion

Jahn, R., Lang, T., & Suedhof, T. C. (2003). Membrane fusion. Cell, 112(4), 519-533. Retrieved from http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WSN-4811J61-B-1&_cdi=7051&_user=38661&_pii=S0092867403001120&_orig=search&_coverDate=02%2F21%2F2003&_sk=998879995&view=c&wchp=dGLbVzb-zSkzS&md5=337489ca709af930fe7d394087229959&ie=/sdarticle.pdf.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0012-F179-1 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0028-9D1D-1
Genre: Journal Article

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 Creators:
Jahn, R.1, Author              
Lang, T.1, Author              
Suedhof, T. C., Author
Affiliations:
1Department of Neurobiology, MPI for biophysical chemistry, Max Planck Society, ou_578595              

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 Abstract: Membrane fusion, one of the most fundamental processes in life, occurs when two separate lipid membranes merge into a single continuous bilayer. Fusion reactions share common features, but are catalyzed by diverse proteins. These proteins mediate the initial recognition of the membranes that are destined for fusion and pull the membranes close together to destabilize the lipid/water interface and to initiate mixing of the lipids. A single fusion protein may do everything or assemblies of protein complexes may be required for intracellular fusion reactions to guarantee rigorous regulation in space and time. Cellular fusion machines are adapted to fit the needs of different reactions but operate by similar principles in order to achieve merging of the bilayers.

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Language(s): eng - English
 Dates: 2003-02-21
 Publication Status: Published in print
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 Rev. Method: Peer
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Title: Cell
Source Genre: Journal
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Pages: - Volume / Issue: 112 (4) Sequence Number: - Start / End Page: 519 - 533 Identifier: -