English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Cerebral proton magnetic resonance spectroscopy of a patient with giant axonal neuropathy

Brockmann, K., Pouwels, P. J. W., Dechent, P., Flanigan, K. M., Frahm, J., & Hanefeld, F. (2003). Cerebral proton magnetic resonance spectroscopy of a patient with giant axonal neuropathy. Brain & Development, 25(1), 45-50. Retrieved from http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6T50-47C3Y0T-5-F&_cdi=4988&_user=38661&_pii=S0387760402001547&_orig=search&_coverDate=01%2F31%2F2003&_sk=999749998&view=c&wchp=dGLbVzb-zSkzV&md5=00e9cd78c8e58a7b83fdba0d55ccbfb7&ie=/sdarticle.pdf.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0012-F1AA-2 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-0EE6-5
Genre: Journal Article

Files

show Files
hide Files
:
17298.pdf (Publisher version), 0B
Name:
17298.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Brockmann, K., Author
Pouwels, P. J. W., Author
Dechent, P.1, Author              
Flanigan, K. M., Author
Frahm, J.1, Author              
Hanefeld, F., Author
Affiliations:
1Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society, ou_578634              

Content

show
hide
Free keywords: magnetic resonance spectroscopy; giant axonal neuropathy; demyelination; leukoencephalopathy
 Abstract: Magnetic resonance imaging of a girl with giant axonal neuropathy revealed a progressive white matter disease. In close agreement with histopathological features reported previously, localized proton magnetic resonance spectroscopy at 9 and 12 years of age indicated a specific damage or loss of axons (reduced N-acetylaspartate and N-acetylaspartylglutamate) accompanied by acute demyelination (elevated choline-containing compounds, myo-inositol, and lactate) in white matter as well as a generalized proliferation of glial cells (elevated choline-containing compounds and myo-inositol) in both gray and white matter. (C) 2002 Elsevier Science B.V. All rights reserved.

Details

show
hide
Language(s): eng - English
 Dates: 2003-01
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Brain & Development
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 25 (1) Sequence Number: - Start / End Page: 45 - 50 Identifier: -