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  Assessment of local brain activation: A simultaneous PET and near-infrared spectroscopy study

Villringer, K., Minoshima, S., Hock, C., Obrig, H., Ziegler, S., Dirnagl, U., et al. (1997). Assessment of local brain activation: A simultaneous PET and near-infrared spectroscopy study. Advances in Experimental Medicine and Biology, 413, 149-153. doi:10.1007/978-1-4899-0056-2_16.

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 Creators:
Villringer, Kersten, Author
Minoshima, S., Author
Hock, C., Author
Obrig, Hellmuth1, Author           
Ziegler, S., Author
Dirnagl, U., Author
Schwaiger, M., Author
Villringer, Arno1, Author           
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1External Organizations, ou_persistent22              

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Free keywords: Positron emission tomography; Cerebral blood flow; Stroop task; Calculation task; NIRS measurement
 Abstract: In five healthy human subjects, near-infrared spectroscopy (NIRS) and positron emission tomography (PET) examinations were performed simultaneously. Changes in [oxy-Hb], [deoxy-Hb] and [total-Hb] as measured by NIRS over the left forehead were compared to measurements of cerebral blood flow by PET during rest and during performance of a calculation task and a Stroop task. When a penetration depth of near-infrared light of 0.9 cm into the brain cortex was assumed, a statistically significant correlation between changes in CBF and changes in [total-Hb] was found. These data confirm the validity of NIRS measurements in human adults.

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 Dates: 1997
 Publication Status: Published in print
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Title: Advances in Experimental Medicine and Biology
Source Genre: Journal
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Pages: - Volume / Issue: 413 Sequence Number: - Start / End Page: 149 - 153 Identifier: -