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  Language dominance assessment by means of fMRI: Contributions from task design, performance, and stimulus modality

Hund-Georgiadis, M., Lex, U., & von Cramon, D. Y. (2001). Language dominance assessment by means of fMRI: Contributions from task design, performance, and stimulus modality. Journal of Magnetic Resonance Imaging, 13(5), 668-675. doi:10.1002/jmri.1094.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-C28B-7 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002C-7DCC-6
Genre: Journal Article

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Hund-Georgiadis, Margret1, Author              
Lex, Ulrike1, Author              
von Cramon, D. Yves1, Author              
Affiliations:
1MPI of Cognitive Neuroscience (Leipzig, -2003), The Prior Institutes, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634574              

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 Abstract: We investigated the influence of different task demands, task designs, and presentation modalities on the functional MRI activation patterns during a language lateralization task in a group of 14 right-handed control subjects. A word classification task was presented as target task appropriate to evoke language-related activation in the inferior frontal gyrus (IFG). The choice of the contrasting baseline task was demonstrated to have a major impact on the functional outcome: While a fixation baseline elicited activations in the inferior frontal gyrus of both hemispheres, a nonsemantic perceptual control task helped to isolate the relevant target task of word classification. The modality of stimulus presentation did not influence the functional data: Auditory and visual presentation modes broadly evoked activations in similar brain regions during word classification. Minor differences in task performance and the side of the responding hand did not interfere with the functional activation patterns of the target task. On the basis of our results, a protocol of functional lateralization in the inferior frontal gyrus is suggested.

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Language(s): eng - English
 Dates: 2001
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: eDoc: 239146
ISI: 000171296300002
Other: P6697
DOI: 10.1002/jmri.1094
 Degree: -

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Title: Journal of Magnetic Resonance Imaging
Source Genre: Journal
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Publ. Info: Chicago, IL : Society for Magnetic Resonance Imaging
Pages: - Volume / Issue: 13 (5) Sequence Number: - Start / End Page: 668 - 675 Identifier: ISSN: 1053-1807
CoNE: https://pure.mpg.de/cone/journals/resource/954925594512