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  MRT-basierte Morphometrie. Eine Bestandsaufnahme

Tittgemeyer, M., & von Cramon, D. Y. (2004). MRT-basierte Morphometrie. Eine Bestandsaufnahme. Nervenarzt, 75(12), 1172-1178. doi:10.1007/s00115-004-1781-9.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-C8E0-2 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002C-2869-D
Genre: Journal Article

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tittgemeyer.pdf (Publisher version), 532KB
 
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 Creators:
Tittgemeyer, Marc1, Author              
von Cramon, D. Yves1, Author              
Affiliations:
1Department Cognitive Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634563              

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Free keywords: Magnetic resonance imaging; Morphometry; Volumetry; Sensitivity
 Abstract: Morphometry offers new approaches for in vivo characterization of many neurolog- ic and psychiatric pathologies. A survey of recent publications only hints at the at- tractiveness of magnetic resonance-based morphometry: published findings are het- erogeneous, partly contradictory, and not always plausible in terms of known neu- ropathologic correlates. Hence, the sensitiv- ity of the applied methods should be ques- tioned. Three parameters affect the vari- ance in morphometric findings: (1) knowl- edge about normal morphologic variabil- ity, (2) confounding physiologic parame- ters, and (3) methodologic misuse. Sound knowledge about the morphologic variabil- ity of the normal brain is vital for the assess- ment of volumetric findings. Large morpho- logic variability may also interfere with the precision of morphometric methods. The multitude of possible confounding physio- logic parameters raises the necessity of pre- cise subject control. Magnetic resonance scanning artefacts require rigid protocols, and application of the rather complex and sensitive methods demands profound in- sight into the techniques.

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Language(s): deu - German
 Dates: 2004
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: eDoc: 239594
Other: P6988
DOI: 10.1007/s00115-004-1781-9
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Title: Nervenarzt
Source Genre: Journal
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Publ. Info: Berlin : Springer-Verlag
Pages: - Volume / Issue: 75 (12) Sequence Number: - Start / End Page: 1172 - 1178 Identifier: ISSN: 0028-2804
CoNE: https://pure.mpg.de/cone/journals/resource/954925427247