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Near-infrare dspectroscopy; Event-related; Stroop
Abstract:
Brai
nactivit
ycanbemonitore
dnon-invasivel
ybynear-infrare
dspectroscop
y(NIRS)
,whic
hhas
severa
ladvantage
sincompariso
nwit
hothe
rimagin
gmethods
,suc
hasflexibility
,portability
,low
cost
an
dbiochemica
lspecificity
.Moreover
,patient
san
dchildre
ncanberepetitivel
yexamined
.Therefore
,the
objectiv
eofthestud
ywa
stotes
tthefeasibilit
yofNIR
Sfortheevent-relate
dapproac
hinfunctiona
lbrain
activatio
nstudie
swit
hcognitiv
eparadigms
.Thus
,change
sintheconcentratio
nofoxy-
,deoxy-
,an
dtotal
hemoglobi
nwer
emeasure
d
byNIR
Sin14health
ysubject
swhil
eperformin
ga
color–wor
d
matching
Stroo
p
tas
k
in
an
event-relate
d
design
.Th
ehemodynami
crespons
e(increas
ein
theconcentratio
n
of
oxy-/tota
lhemoglobi
n
an
d
decreas
ein
theconcentratio
n
ofdeoxy-hemoglobin
)wa
sstronge
rduring
incongruen
tcompare
dtocongruen
tan
dneutra
ltrial
softheStroo
ptas
kinthelatera
lprefronta
lcortex
bilaterally
.Thi
sstronge
rhemodynami
crespons
ewa
sinterprete
dasa
stronge
rbrai
nactivatio
nduring
incongruen
ttrial
softheStroo
ptask
,du
etointerference
.A
ne
w
metho
dforNIR
Sdat
aevaluatio
nthat
enable
stheanalysi
softhehemodynami
crespons
etoeac
hsingl
etria
lisintroduced
.Eac
hhemodynamic
respons
ewa
scharacterize
dbytheparameter
sgain
,lagan
ddispersio
nofa
Gaussia
nfunctio
nfitte
dby
nonlinea
rregression
.Specifi
cdifference
sbetwee
ntheincongruen
tan
dneutra
lconditio
nwer
efoun
dfor
gai
nan
dlag
.Further
,thes
eparameter
swer
ecorrelate
dwit
hthebehaviora
lperformance
.Inconclusion,
brai
nactivit
yma
ybestudie
d
byNIR
Susin
gcognitiv
estimul
iinanevent-relate
d
design
.