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  Use of short intertrial intervals in single-trial experiments: A 3T fMRI-study

Pollmann, S., Wiggins, C. J., Norris, D. G., von Cramon, D. Y., & Schubert, T. (1998). Use of short intertrial intervals in single-trial experiments: A 3T fMRI-study. NeuroImage, 8(4), 327-339. doi:10.1006/nimg.1998.0373.

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 Urheber:
Pollmann, Stefan1, Autor           
Wiggins, Christopher J.1, Autor           
Norris, David G.1, Autor           
von Cramon, D. Yves1, Autor           
Schubert, Torsten1, Autor           
Affiliations:
1MPI of Cognitive Neuroscience (Leipzig, -2003), The Prior Institutes, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634574              

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 Zusammenfassung: We investigated the detectability of task-related changes in the fMRI-signal in an averaged single trial design under systematic variation of intertrial intervals (ITI) in the range between 4 and 12 s. Investigation of the signal timecourses showed a shortening of the baseline period and subsequently a reduction in signal amplitude with decreasing ITI. The main finding is that effect size, i.e., the ratio of task-related signal changes and error variance remained approximately constant from ITI of 12 s down to 6 s. At ITI = 4 s, the effect size was reduced by about 50%. The effects of ITI reduction were comparable in all six cortical ROI which were analyzed. In two subcortical ROI, effect size was already reduced at longer ITI. At ITI = 4 s, the rising flank of the BOLD response was delayed compared to longer ITI. When the data were corrected for the temporal overlap of successive BOLD-responses, the signal amplitudes at ITI = 4 s were comparable to the amplitudes measured at an interval of 12 s. This indicated that the amplitude reduction was mainly due to a linear superposition of the contiguous BOLD-responses.

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Sprache(n): eng - English
 Datum: 1998
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: eDoc: 239455
ISI: 000077306700002
DOI: 10.1006/nimg.1998.0373
 Art des Abschluß: -

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Titel: NeuroImage
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: Orlando, FL : Academic Press
Seiten: - Band / Heft: 8 (4) Artikelnummer: - Start- / Endseite: 327 - 339 Identifikator: ISSN: 1053-8119
CoNE: https://pure.mpg.de/cone/journals/resource/954922650166