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  Interaction between the bio-surfactant Surfactin and lipid membranes - COLL 310

Holzwarth, J. F., Kell, H., Couderc-Azouani, S., Vater, J., Dietrich, U., Heenan, R., et al. (2004). Interaction between the bio-surfactant Surfactin and lipid membranes - COLL 310. Abstracts of Papers of the American Chemical Society, 227, U853-U853.

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Datensatz-Permalink: https://hdl.handle.net/11858/00-001M-0000-0011-0E05-9 Versions-Permalink: https://hdl.handle.net/11858/00-001M-0000-0011-0E06-7
Genre: Konferenzbeitrag

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 Urheber:
Holzwarth, Josef F.1, Autor           
Kell, Henny1, Autor           
Couderc-Azouani, Sabine1, Autor           
Vater, Joachim, Autor
Dietrich, Undine, Autor
Heenan, Richard, Autor
Gutberlet, Thomas, Autor
Penfold, Jeffery, Autor
Boettcher, Christoph, Autor
Affiliations:
1Physical Chemistry, Fritz Haber Institute, Max Planck Society, ou_634546              

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Schlagwörter: –
 Zusammenfassung: The bio-surfactant Surfactin possesses antifungal, antiviral and antitumural properties. We investigated the interaction of Surfactin with lipid monolayers and vesicles applying differential scanning calorimetry (DSC), static light scattering, cryo-transmission electron microscopy (TEM) fluorescence microscopy and small angle neutron scattering (SANS). Our target was to clarify how lipid membranes are influenced by the insertion of different amounts of Surfactin: This should lead to a better understanding of the biological function of Surfactin. Low concentrations of Surfactin were solubilized in monolayers or vesibles of L-a-Di-myristoylphosphatidylcholine (DMPC) or L-a-Dipalmitoylphosphatidylcholine (DPPC) and normal phase transition behavior was observed. In the range from 4–20 % of Surfactin to lipid increasing heysteresis was characteristic for the phase behavior. At higher concentrations of Surfactin the vesicles disintegrated into mixed micelles. In addition to the thermodynamic and structural investigations we also performed temperature-jump experiments to learn about the dynamics of the lipid-Surfactin system.

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Sprache(n): eng - English
 Datum: 2004
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: eDoc: 208314
URI: http://oasys2.confex.com/acs/227nm/techprogram/P713157.HTM
 Art des Abschluß: -

Veranstaltung

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Titel: 227th ACS National Meeting – Division of Colloid and Surface Chemistry. Symposium in Memory of Arthur W. Adamson
Veranstaltungsort: Anaheim, CA
Start-/Enddatum: 2004-03-28 - 2004-04-01

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Titel: Abstracts of Papers of the American Chemical Society
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: American Chemical Society
Seiten: - Band / Heft: 227 Artikelnummer: - Start- / Endseite: U853 - U853 Identifikator: ISBN: 0-8412-3925-8
ISSN: 0065-7727