English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
  Interhemispheric interactions between the human primary somatosensory cortices

Ragert, P., Nierhaus, T., Cohen, L. G., & Villringer, A. (2011). Interhemispheric interactions between the human primary somatosensory cortices. PLoS One, 6(2): e16150. doi:10.1371/journal.pone.0016150.

Item is

Files

show Files
hide Files
:
Ragert_InterhemisphericInteractions.pdf (Publisher version), 271KB
Name:
Ragert_InterhemisphericInteractions.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
2011
Copyright Info:
© 2011 Ragert et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Locators

show

Creators

show
hide
 Creators:
Ragert, Patrick1, Author              
Nierhaus, Till1, 2, Author              
Cohen, Leonardo G.3, Author
Villringer, Arno1, 2, 4, Author              
Affiliations:
1Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
2Berlin Neuroimaging Center (BNIC) and Department of Neurology, Charite, Berlin, Germany, ou_persistent22              
3Human Cortical Physiology Section (HCPS), National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, Maryland, USA, ou_persistent22              
4Berlin School of Mind and Brain, Humboldt University, Berlin, Germany, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: In the somatosensory domain it is still unclear at which processing stage information reaches the opposite hemispheres. Due to dense transcallosal connections, the secondary somatosensory cortex (S2) has been proposed to be the key candidate for interhemispheric information transfer. However, recent animal studies showed that the primary somatosensory cortex (S1) might as well account for interhemispheric information transfer. Using paired median nerve somatosensory evoked potential recordings in humans we tested the hypothesis that interhemispheric inhibitory interactions in the somatosensory system occur already in an early cortical processing stage such as S1. Conditioning right S1 by electrical median nerve (MN) stimulation of the left MN (CS) resulted in a significant reduction of the N20 response in the target (left) S1 relative to a test stimulus (TS) to the right MN alone when the interstimulus interval between CS and TS was between 20 and 25 ms. No such changes were observed for later cortical components such as the N20/P25, N30, P40 and N60 amplitude. Additionally, the subcortically generated P14 response in left S1 was also not affected. These results document the existence of interhemispheric inhibitory interactions between S1 in human subjects in the critical time interval of 20–25 ms after median nerve stimulation.

Details

show
hide
Language(s): eng - English
 Dates: 2010-12-132011-02-10
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1371/journal.pone.0016150
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: PLoS One
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: San Francisco, CA : Public Library of Sciene
Pages: - Volume / Issue: 6 (2) Sequence Number: e16150 Start / End Page: - Identifier: ISSN: 1932-6203
CoNE: https://pure.mpg.de/cone/journals/resource/1000000000277850