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Corruption of host seven-transmembrane proteins by pathogenic microbes: a common theme in animals and plants?

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Panstruga,  R.
Dept. of Plant Microbe Interactions (Paul Schulze-Lefert), MPI for Plant Breeding Research, Max Planck Society;

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Schulze-Lefert,  P.
Dept. of Plant Microbe Interactions (Paul Schulze-Lefert), MPI for Plant Breeding Research, Max Planck Society;

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Zitation

Panstruga, R., & Schulze-Lefert, P. (2003). Corruption of host seven-transmembrane proteins by pathogenic microbes: a common theme in animals and plants? Microbes and Infection, 5(5), 429-437.


Zitierlink: https://hdl.handle.net/11858/00-001M-0000-0012-3CE7-A
Zusammenfassung
Human diseases like AIDS, malaria, and pneumonia are caused by pathogens that corrupt host chemokine G-protein coupled receptors for molecular docking. Comparatively, little is known about plant host factors that are required for pathogenesis and that may serve as receptors for the entry of pathogenic microbes. Here, we review potential analogies between human chemokine receptors and the plant seven-transmembrane MLO protein, a candidate serving a dual role as docking molecule and defence modulator for the phytopathogenic powdery mildew fungus. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.