English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Two ancient classes of MIKC-type MADS-box genes are present in the moss Physcomitrella patens

MPS-Authors
/persons/resource/persons40175

Saedler,  H.
Dept. of Molecular Plant Genetics (Heinz Saedler), MPI for Plant Breeding Research, Max Planck Society;

/persons/resource/persons40110

Munster,  T.
Dept. of Molecular Plant Genetics (Heinz Saedler), MPI for Plant Breeding Research, Max Planck Society;

/persons/resource/persons40235

Theissen,  G.
Dept. of Molecular Plant Genetics (Heinz Saedler), MPI for Plant Breeding Research, Max Planck Society;

Locator
There are no locators available
Fulltext (public)
There are no public fulltexts available
Supplementary Material (public)
There is no public supplementary material available
Citation

Henschel, K., Kofuji, R., Hasebe, M., Saedler, H., Munster, T., & Theissen, G. (2002). Two ancient classes of MIKC-type MADS-box genes are present in the moss Physcomitrella patens. Molecular Biology and Evolution, 19(6), 801-814.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0012-3DCF-9
Abstract
Characterization of seven MADS-box genes, termed PPM1-PPM4 and PpMADS1-PIWADS3, from the moss model species Physcomitrella patens is reported. Phylogeny reconstructions and comparison of exon-intron structures revealed that the genes described here represent two different classes of homologous, yet distinct, MIKC-type MADS-box genes, termed MIKCc-type genes-"(c)"stands for "classic"-(PPM1, PPM2, PpMADS/) and MIKC*type genes (PPM3, PPM4, PpMADS2. PpMADS3). The two gene classes deviate from each other in a characteristic way, especially in a sequence stretch termed intervening region, MIKCc-type genes are abundantly present in all land plants which have been investigated in this respect. and give rise to well-known gene types such as floral meristem and organ identity genes. In contrast, L4MB1 from the clubmoss Lycopodium annotintan was identified as the only other MIKC*-Lype gene published so far. Our findings strongly suggest that the most recent common ancestor of mosses and vascular plants contained at least one MIKCc-type and one MIKC*-type gene. Our studies thus reveal an ancient duplication of an MIKC-type gene that occurred before the separation of the lineages that led to extant mosses and vascular plants more than about 450 MYA. The identification of bona fide K-domains in both MIKCc-type and MIKCc-type proteins suggests that the K- domain is more ancient than is suggested by a recent alternative hypothesis. MIKC"-type genes may have escaped identification in ferns and seed plants so far. It seems more likely, however, that they represent a class of genes which has been lost in the lineage which led to extant ferns and seed plants. The high number of P. patens MADS-box genes and the presence of a K-box in the coding region and of some potential binding sites for MADS-domain proteins and other transcription factors in the putative promoter regions of these genes suggest that MADS-box genes in mosses are involved in complex gene regulatory networks similar to those in flowering plants.