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Journal Article

Reduced muscle contraction and a relaxed posture during sleep-like Lethargus.

MPS-Authors
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Schwarz,  J.
Research Group of Sleep and Waking, MPI for biophysical chemistry, Max Planck Society;

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Spies,  J. P.
Research Group of Sleep and Waking, MPI for biophysical chemistry, Max Planck Society;

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Bringmann,  H.
Research Group of Sleep and Waking, MPI for biophysical chemistry, Max Planck Society;

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Citation

Schwarz, J., Spies, J. P., & Bringmann, H. (2012). Reduced muscle contraction and a relaxed posture during sleep-like Lethargus. Worm, 1(1), 1-3. doi:10.4161/worm.19499.


Cite as: http://hdl.handle.net/11858/00-001M-0000-000F-83A7-7
Abstract
Sleep is characterized by reduced muscle activity resulting in reduced movement and a typical posture compatible with relaxed muscles. Prior to each molt, C.elegans larvae go through a phase of behavioral quiescence called Lethargus. Lethargus has sleep-like properties, but a specific posture has not yet been described. Do C.elegans larvae relax their muscles during sleep and do they assume a typical posture? We measured worm posture and body wall muscle activity using calcium imaging across the sleep-wake-like cycle. We found that worms were less curved and had less muscle activity during the sleep-like state. We conclude that during Lethargus, muscle activity is reduced, resulting in a relaxed body posture typical for a sleep-like state.