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A Catalytic Approach to (R)-(+)-Muscopyridine with Integrated "Self-Clearance"

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Fürstner,  Alois
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Leitner,  Andreas
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Citation

Fürstner, A., & Leitner, A. (2003). A Catalytic Approach to (R)-(+)-Muscopyridine with Integrated "Self-Clearance". Angewandte Chemie International Edition, 42(3), 308-311. doi:10.1002/anie.200390103.


Cite as: https://hdl.handle.net/11858/00-001M-0000-000F-98D7-1
Abstract
The integration of various metal-catalyzed reactions into a one-pot processes opens an unprecedentedly short and efficient route to the odoriferous alkaloid (R)-(+)-muscopyridine. Importantly, it is shown how metathesis can be used for a most convenient “self-clearance” of a product mixture (see scheme; OTf=CF3SO3).