English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Drug release from biodegradable silica fibers

MPS-Authors
/persons/resource/persons58699

Kleitz,  F.
Research Department Schüth, Max-Planck-Institut für Kohlenforschung, Max Planck Society;
Research Department Schüth, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58760

Linden,  M.
Research Department Schüth, Max-Planck-Institut für Kohlenforschung, Max Planck Society;
Research Department Schüth, Max-Planck-Institut für Kohlenforschung, Max Planck Society;
Research Department Schüth, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Ressource
No external resources are shared
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Czuryszkiewicz, T., Ahvenlammi, J., Kortesuo, P., Ahola, M., Kleitz, F., Jokinen, M., et al. (2002). Drug release from biodegradable silica fibers. Journal of Non-Crystalline Solids, 306(1), 1-10. doi:10.1016/S0022-3093(02)01060-8.


Cite as: http://hdl.handle.net/11858/00-001M-0000-000F-99C4-3
Abstract
Sol-gel derived biodegradable SiO2 gel fibers have been prepared and characterized by Raman spectroscopy, SEM, Si-29 MAS NMR and TG=MS, respectively. An active component, dexmedetomidine hydrochloride, was incorporated in situ into the fiber structure, by adding it to the sol used for fiber spinning. The subsequent release of the active component was studied in vitro and shown to be determined by differences in the fiber structure, for which clear but indirect evidence was obtained from the different characterization methods used. (C) 2002 Published by Elsevier Science B.V.