Revisiting regression in autism: Heller's dementia infantilis

Westphal, Alexander; Schelinski, Stefanie; Volkmar, Fred; Pelphrey, Kevin

doi:10.1007/s10803-012-1559-z

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Revisiting regression in autism: Heller's dementia infantilis

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Schelinski, Stefanie
Child Study Center, Yale University, New Haven, CT, USA;
Max Planck Research Group Neural Mechanisms of Human Communication, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Citation

Westphal, A., Schelinski, S., Volkmar, F., & Pelphrey, K. (2013). Revisiting regression in autism: Heller's dementia infantilis. Journal of Autism and Developmental Disorders, 43(2), 265-271. doi:10.1007/s10803-012-1559-z.

Cite as: https://hdl.handle.net/11858/00-001M-0000-000F-EDA8-A

Abstract

Theodor Heller first described a severe regression of adaptive function in normally developing children, something he termed dementia infantilis, over one 100 years ago. Dementia infantilis is most closely related to the modern diagnosis, childhood disintegrative disorder. We translate Heller’s paper, Über Dementia Infantilis, and discuss similarities in presentation between Heller’s cases, and a group of children with childhood disintegrative disorder. In particular we discuss a prodromal period of affective dysregulation described by Heller, and also evident in our sample, but not previously described in any detail since the publication of Über Dementia Infantilis.