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Electron tomography: towards visualizing the molecular organization of the cytoplasm

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Baumeister,  W.
Baumeister, Wolfgang / Molecular Structural Biology, Max Planck Institute of Biochemistry, Max Planck Society;

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Citation

Baumeister, W. (2002). Electron tomography: towards visualizing the molecular organization of the cytoplasm. Current Opinion in Structural Biology, 12(5), 679-684.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0010-6E32-F
Abstract
Electron tomography of thin sections of plastic-em bedded biological material provides valuable insights into the organellar organization of cells, With the advent of automated data-acquisition procedures, it has become possible to study radiation-sensitive specimens, such as frozen-hydrated organelles and whole cells. This opens up exciting perspectives for visualizing the molecular organization of the cytoplasm.