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Journal Article

Short-term volume and turgor regulation in yeast


Schaber,  Jörg
Max Planck Society;


Klipp,  Edda
Independent Junior Research Groups (OWL), Max Planck Institute for Molecular Genetics, Max Planck Society;

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Schaber, J., & Klipp, E. (2008). Short-term volume and turgor regulation in yeast. Essays in Biochemisry, 45, 147-159. Retrieved from http://essays.biochemistry.org/bsessays/045/bse0450147.htm.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0010-80EE-6
Volume is a highly regulated property of cells, because it critically affects intracellular concentration. In the present chapter, we focus on the short-term volume regulation in yeast as a consequence of a shift in extracellular osmotic conditions. We review a basic thermodynamic framework to model volume and solute flows. In addition, we try to select a model for turgor, which is an important hydrodynamic property, especially in walled cells. Finally, we demonstrate the validity of the presented approach by fitting the dynamic model to a time course of volume change upon osmotic shock in yeast.