Recent advances of protein microarrays

Hultschig, Claus; Kreutzberger, Jürgen; Seitz, Harald; Konthur, Zoltán; Büssow, Konrad; Lehrach, Hans

doi:10.1016/j.cbpa.2005.12.011

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Recent advances of protein microarrays

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Hultschig, Claus
Max Planck Society;

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Kreutzberger, Jürgen
Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society;

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Seitz, Harald
Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society;

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Konthur, Zoltán
In vitro Ligand Screening (Zoltán Konthur), Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society;

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Büssow, Konrad
Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society;

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Lehrach, Hans
Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society;

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Citation

Hultschig, C., Kreutzberger, J., Seitz, H., Konthur, Z., Büssow, K., & Lehrach, H. (2006). Recent advances of protein microarrays. Current Opinion in Chemical Biology, 10(1), 4-10. doi:10.1016/j.cbpa.2005.12.011.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0010-84B0-3

Abstract

Technological innovations and novel applications have greatly advanced the field of protein microarrays. Over the past two years, different types of protein microarrays have been used for serum profiling, protein abundance determinations, and identification of proteins that bind DNA or small compounds. However, considerable development is still required to ensure common quality standards and to establish large content repertoires. Here, we summarize applications available to date and discuss recent technological achievements and efforts on standardization.