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Miniaturization in functional genomics and proteomics

MPG-Autoren
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Sauer,  Sascha
Nutrigenomics and Gene Regulation (Sascha Sauer), Independent Junior Research Groups (OWL), Max Planck Institute for Molecular Genetics, Max Planck Society;

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Lange,  Bodo M. H.
Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society;

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Gobom,  Johan
Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society;

Nyarsik,  Lajos
Max Planck Society;

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Seitz,  Harald
Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society;

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Lehrach,  Hans
Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society;

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Volltexte (frei zugänglich)

Sauer et al. - Nat Rev Genet.pdf
(beliebiger Volltext), 2MB

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Zitation

Sauer, S., Lange, B. M. H., Gobom, J., Nyarsik, L., Seitz, H., & Lehrach, H. (2005). Miniaturization in functional genomics and proteomics. Nature Reviews Genetics, 6(6), 465-476. doi:doi:10.1038/nrg1618.


Zitierlink: http://hdl.handle.net/11858/00-001M-0000-0010-8631-F
Zusammenfassung
Proteins are the key components of the cellular machinery responsible for processing changes that are ordered by genomic information. Analysis of most human proteins and nucleic acids is important in order to decode the complex networks that are likely to underlie many common diseases. Significant improvements in current technology are also required to dissect the regulatory processes in high-throughtput and with low cost. Miniaturization of biological assays is an important prerequisite to achieve these goals in the near future.