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Journal Article

Hip1 and Hippi Participate in a Novel Cell Death-Signaling Pathway

MPS-Authors

Wanker,  Erich E.
Max Planck Society;

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Citation

Wanker, E. E. (2002). Hip1 and Hippi Participate in a Novel Cell Death-Signaling Pathway. Develomental Cell, 2, 126-128.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0010-8C62-D
Abstract
Neuronal apoptosis is a cardinal feature of late-onset neurodegenerative disorders such as Alzheimer's and Huntington's disease. Biochemical and cell biological studies point to a role for Hip1 and Hippi in caspase-8 activation and the initiation of apoptosis during the pathogenesis of Huntington's disease.