SpliceNest: visualizing gene structure and alternative splicing based on EST 
clusters

Coward, Eivind; Haas, Stefan A.; Vingron, Martin

Datensatz

DATENSATZ AKTIONENEXPORT

Zur Ablage hinzufügen

Lokale TagsFreigabegeschichteDetailsÜbersicht

Freigegeben

Zeitschriftenartikel

SpliceNest: visualizing gene structure and alternative splicing based on EST clusters

MPG-Autoren

Coward, Eivind
Max Planck Society;

Haas, Stefan A.
Max Planck Society;

/persons/resource/persons50613

Vingron, Martin
Gene regulation (Martin Vingron), Dept. of Computational Molecular Biology (Head: Martin Vingron), Max Planck Institute for Molecular Genetics, Max Planck Society;

Externe Ressourcen

Es sind keine externen Ressourcen hinterlegt

Volltexte (beschränkter Zugriff)

Für Ihren IP-Bereich sind aktuell keine Volltexte freigegeben.

Volltexte (frei zugänglich)

Es sind keine frei zugänglichen Volltexte in PuRe verfügbar

Ergänzendes Material (frei zugänglich)

Es sind keine frei zugänglichen Ergänzenden Materialien verfügbar

Zitation

Coward, E., Haas, S. A., & Vingron, M. (2002). SpliceNest: visualizing gene structure and alternative splicing based on EST clusters. Trends in Genetics, 18(1), 53-55.

Zitierlink: https://hdl.handle.net/11858/00-001M-0000-0010-8C7C-8

Zusammenfassung

Messenger RNA sequences, expressed sequence tags (ESTs), and, in particular, consensus sequences of clustered ESTs provide valuable information about splice variants of genes. We have mapped such (predicted) human mRNA sequences onto human genomic DNA to compute gene structure and splice variants. The results of this computation have been collected in a public database, SpliceNest, with a web-based, interactive graphical user interface. The quality of the presented data profits from previous assembly of ESTs and allows for analysis of gene structure and detection of splice variants in conjunction with the clones and libraries that indicated variants. A new, web-accessible database, SpliceNest, contains predicted human gene structure and splice variants derived from human mRNAs and coding sequences predicted from EST assemblies and mapped onto genomic DNA.