Finding one's way in proteomics: a protein species nomenclature

Schlüter, Hartmut; Apweiler, Rolf; Holzhütter, Hermann-Georg; Jungblut, Peter R.

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Finding one's way in proteomics: a protein species nomenclature

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Jungblut, Peter R.
Core Facilities / Proteinanalysis, Max Planck Institute for Infection Biology, Max Planck Society;

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Chem_Centr_J_2009_3_11.pdf
(出版社版), 260KB

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引用

Schlüter, H., Apweiler, R., Holzhütter, H.-G., & Jungblut, P. R. (2009). Finding one's way in proteomics: a protein species nomenclature. Chemistry Central Journal, 3:.

引用: https://hdl.handle.net/11858/00-001M-0000-000E-C0AB-A

要旨

Our knowledge of proteins has greatly improved in recent years, driven by new technologies in the fields of molecular biology and proteome research. It has become clear that from a single gene not only one single gene product but many different ones - termed protein species - are generated, all of which may be associated with different functions. Nonetheless, an unambiguous nomenclature for describing individual protein species is still lacking. With the present paper we therefore propose a systematic nomenclature for the comprehensive description of protein species. The protein species nomenclature is flexible and adaptable to every level of knowledge and of experimental data in accordance with the exact chemical composition of individual protein species. As a minimum description the entry name (gene name + species according to the UniProt knowledgebase) can be used, if no analytical data about the target protein species are available.