English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Journal Article

Evaluation of the potential of nonlinear gradients for separating a ternary mixture

MPS-Authors
/persons/resource/persons86271

Damtew Hamza,  Andualem
Otto-von-Guericke-Universität Magdeburg, External Organizations;
Physical and Chemical Foundations of Process Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society;

/persons/resource/persons86488

Sreedhar,  B.
Physical and Chemical Foundations of Process Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society;
International Max Planck Research School (IMPRS), Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society;

/persons/resource/persons86477

Seidel-Morgenstern,  A.
Physical and Chemical Foundations of Process Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society;
Otto-von-Guericke-Universität Magdeburg, External Organizations;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Damtew Hamza, A., Sreedhar, B., & Seidel-Morgenstern, A. (2009). Evaluation of the potential of nonlinear gradients for separating a ternary mixture. Journal of Chromatography A, 1216(28), 5355-5364. doi:10.1016/j.chroma.2009.05.026.


Cite as: https://hdl.handle.net/11858/00-001M-0000-0013-9389-7
Abstract
The potential of applying nonlinear gradients in preparative chromatography is evaluated theoretically and experimentally. The second eluting component of a ternary model mixture is considered as the target component. Systematic gradient resolution experiments were conducted for this mixture using reversed phase chromatography. In preliminary experimental investigations the effect of the mobile phase composition on the specific distribution equilibria was quantified. Concave and convex solvent strength gradients were analysed and compared with conventional linear gradients. Main result of the study is the fact that significant improvement in productivity can be achieved if the gradient shapes are designed carefully. Copyright © 2009 Elsevier B.V. All rights reserved. [accessed July 27, 2009]