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Meeting Abstract

Functional Quantitative Susceptibility Mapping (fQSM)

MPS-Authors
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Balla,  DZ
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Hagberg,  G
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Balla, D., Sanchez-Panchuelo, R., Wharton, S., Hagberg, G., Scheffler, K., Francis, S., et al. (2012). Functional Quantitative Susceptibility Mapping (fQSM). In 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012).


Cite as: https://hdl.handle.net/11858/00-001M-0000-0013-B7C4-7
Abstract
Quantitative susceptibility mapping (QSM) was performed on fMRI time-series to reconstruct maps with activation induced local susceptibility changes. A multi-step image processing algorithm was developed for filtering out unwanted temporal and spatial signal variations. The method was validated on GE-EPI BOLD-fMRI datasets acquired at 7T with 1mm isotropic resolution during the application of visual, motor and somatosensory activation paradigms. Series of high-quality phase and susceptibility maps with minimal temporal noise were reconstructed, which resulted in activation maps corresponding to estimations from the modulus data. Functional QSM (fQSM) allows for quantification of the BOLD-effect for any time-series with phase information.