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Journal Article

An aryl-phosphonate appended macrocyclic platform for lanthanide based bimodal imaging agents

MPS-Authors
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Placidi,  MP
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Engelmann,  J
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Logothetis,  NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Angelovski,  G
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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http://pubs.rsc.org/en/content/articlepdf/2011/cc/c1cc14437e
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Citation

Placidi, M., Engelmann, J., Natrajan, L., Logothetis, N., & Angelovski, G. (2011). An aryl-phosphonate appended macrocyclic platform for lanthanide based bimodal imaging agents. Chemical Communications, 47(41), 11534-11536. doi:10.1039/C1CC14437E.


Cite as: https://hdl.handle.net/11858/00-001M-0000-0013-BA1E-1
Abstract
Four ligand systems have been prepared whose characteristics are well suited to the design of bimodal MRI and luminescence probes. The lanthanide complexes display high relaxivities and luminescence quantum yields. These properties are retained at higher magnetic fields and in a range of competitive environments including model extracellular medium and cultured cells.