Human fMRI at 9.4 T: Preliminary Results

Budde, J; Mühlbauer, F; Shajan, G; Zaitsev, M; Pohmann, R

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Human fMRI at 9.4 T: Preliminary Results

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Budde, J
Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Mühlbauer, F
Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Shajan, G
Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Pohmann, R
Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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引用

Budde, J., Mühlbauer, F., Shajan, G., Zaitsev, M., & Pohmann, R. (2011). Human fMRI at 9.4 T: Preliminary Results. Poster presented at 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.

引用: https://hdl.handle.net/11858/00-001M-0000-0013-BC02-D

要旨

With increasing field, the MR signal-to-noise ratio is expected to grow linearly, while a BOLD increase of more than linear is expected [1]. In addition, a higher emphasis on signal from microvasculature is predicted, especially for SE-EPI [2,3], while GE - EPI remains more specific to the macrovasculature. Here, a field strength of 9.4 T is used for the first time to measure BOLD activation during finger tapping of a human subject. To examine the signal contributions of tissue and veins, the functional maps were overlaid on T2*-weighted GRE images revealing venous vasculature at high detail. Co-registration of both image modalities demonstrates where the functional signal coincides with venous structures.