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In vivo chlorine-35, sodium-23 and proton magnetic resonance imaging of the rat brain

MPS-Authors
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Augath,  M
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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ISMRM-2010-981.PDF
(Any fulltext), 620KB

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Citation

Kirsch, S., Augath, M., Seiffge, D., Schilling, R., & Schad, L. (2010). In vivo chlorine-35, sodium-23 and proton magnetic resonance imaging of the rat brain. Poster presented at ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-C07E-F
Abstract
Chloride (Cl-) is the most abundant anion in the mammal organism playing an important role in many cellular processes. For instance, plasma membrane Cl- currents are important for the regulation of excitability in nerve and muscle. Moreover, Cl- ions play a crucial role in controlling the ionic composition of the cytoplasm and the volume of cells [1]. In order to investigate the feasibility of combined in vivo 35Cl, 23Na and 1H MRI we developed a rf coil setup to measure 35Cl, 23Na and 1H signals in one scanning session without moving the subject or changing the setup.