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Comparison of Pulsed Arterial Spin Labeling Sequences Using Different Absolute Quantification Methods

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Cavusoglu,  M
Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Uludag,  K
Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Cavusoglu, M., Ugurbil, K., & Uludag, K. (2008). Comparison of Pulsed Arterial Spin Labeling Sequences Using Different Absolute Quantification Methods. Poster presented at 16th Scientific Meeting and Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2008), Toronto, Canada.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-C997-9
Abstract
Three different ASL schemes (Q2TIPS, FAIR-QUIPSSII and PICORE-QUIPSSII with asymmetric BASSI pulses) were compared measuring absolute cerebral blood flow (CBF) in the human brain at 3T. Signal-to-noise ratios (SNR), magnetization difference between control and tag images and three different absolute CBF quantification schemes were evaluated. For identical sequence parameters and voxels, it was found that a) FAIR-QUIPSSII has the highest SNR b) FAIR-QUIPSSII yields slightly higher CBF values c) absolute CBF values depend on the quantification scheme utilized. One possible explanation for the findings is that effective labeling efficiency and physiological noise contamination are different for the tagging procedures used.