Dynamics of Lactate Concentration and BOLD Effect Upon Repeated Identical 
Visual Stimuli

Mangia, S; Tkac, I; Logothetis, NK; Van de Moortele , P-F; Gruetter, R; Ugurbil, K

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Poster

Dynamics of Lactate Concentration and BOLD Effect Upon Repeated Identical Visual Stimuli

MPS-Authors

/persons/resource/persons84063

Logothetis, NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

External Resource

https://cds.ismrm.org/ismrm-2007/files/1_program.pdf
(Abstract)

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Mangia, S., Tkac, I., Logothetis, N., Van de Moortele, P.-F., Gruetter, R., & Ugurbil, K. (2007). Dynamics of Lactate Concentration and BOLD Effect Upon Repeated Identical Visual Stimuli. Poster presented at 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0013-CDD5-E

Abstract

In vivo 1H NM spectroscopy at 7 T was utilized to measure the changes of lactate concentration upon repeated identical visual stimuli, each lasting 2 min. The amplitude of these changes was attenuated from the initial value of 0.2 μmol/g and gradually disappeared in the noise. In sharp contrast, the Blood Oxygen Level Dependent (BOLD) effect was persistent during the whole paradigm. This finding may suggest a differential adaptation of cortical output that
is not reflected at the level of the global excitation-inhibition activity of the cortical canonical circuits.