Spin-echo fMRI of the temporal lobe in awake, behaving monkeys at 7T

Goense, JBM; Ku, S-P; Merkle, H; Tolias, AS; Logothetis, NK

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Spin-echo fMRI of the temporal lobe in awake, behaving monkeys at 7T

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Goense, JBM
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Ku, S-P
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Merkle, H
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Tolias, AS
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Logothetis, NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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引用

Goense, J., Ku, S.-P., Merkle, H., Tolias, A., & Logothetis, N. (2007). Spin-echo fMRI of the temporal lobe in awake, behaving monkeys at 7T. Poster presented at 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany.

引用: https://hdl.handle.net/11858/00-001M-0000-0013-CDE9-2

要旨

Susceptibility gradients from the ear canal result in distortion and signal loss in GE-EPI, resulting in loss of functional activation in areas adjacent to the ear canal. Although susceptibility-related signal loss also occurs at low field, at 7T it is so severe that no functional activation is seen in these areas. We are interested in fMRI of the entire visual ventral stream in awake monkeys, because the ventral pathway is crucial for object recognition. To overcome the susceptibility problem in the temporal lobes, we used SE-EPI, which allowed us to recover functional activation in areas affected by susceptibility gradients.