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The effect of post labeling delay on specificity of the fCBF signal in monkey striate cortex

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Zappe,  A-C
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Goense,  JBM
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Logothetis,  NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Pfeuffer,  J
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Zappe, A.-C., Goense, J., Logothetis, N., & Pfeuffer, J. (2006). The effect of post labeling delay on specificity of the fCBF signal in monkey striate cortex. Talk presented at 23rd Annual Scientific Meeting of the ESMRMB 2006. Warsaw, Poland.


Cite as: https://hdl.handle.net/11858/00-001M-0000-0013-D021-D
Abstract
Activation maps acquired with perfusion-based FMRI are known to be more specific to the parenchyma and less sensitive to proximal draining veins compared to BOLD [1]. Here, the specificity of ASL activation maps in the nonhuman primate was investigated at high spatial resolution. Since the choice of labeling parameters can affect the specificity of the measured activation, the influence of the post-labeling-delay (PLD) and labeling-time (LT) on perfusion-based activation maps was evaluated.