Physicochemical Characterization of the Strychnos Alkaloids by Capillary Zone 
Electrophoresis

Fu, S; Zhang, F; Zhang, X; Xu, Q; Xiao, H; Liang, X

doi:10.2116/analsci.21.1303

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Physicochemical Characterization of the Strychnos Alkaloids by Capillary Zone Electrophoresis

MPS-Authors

There are no MPG-Authors in the publication available

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Fu, S., Zhang, F., Zhang, X., Xu, Q., Xiao, H., & Liang, X. (2005). Physicochemical Characterization of the Strychnos Alkaloids by Capillary Zone Electrophoresis. Analytical Sciences, 21(11), 1303-1308. doi:10.2116/analsci.21.1303.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0013-D399-7

Abstract

A capillary zone electrophoresis (CZE) method has been developed for investigating the physicochemical characteristics of five Strychnos alkaloids in Strychnos nux-vomica L. Firstly, the dissociation constants of the five Strychnos alkaloids were determined, based on the relation between the effective mobility of the solutes and the buffer pH. The mathematical relationship was strictly deduced from the fundamental electrophoretic theory and the dissociation equilibrium. Secondly, an equation describing the relation between the migration time of alkaloids of similar structure and their molecular weights was developed and used to predict the migration order and to calculate the electrosomotic velocity. The results predicted by the theory agreed with those from experiments.