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Localized 1H MR spectroscopy in the alert monkey at 7 Tesla

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Pfeuffer,  J
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Juchem,  C
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Logothetis,  NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Pfeuffer, J., Juchem, C., Merkle, H., & Logothetis, N. (2005). Localized 1H MR spectroscopy in the alert monkey at 7 Tesla. In 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005).


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-D5A7-6
Abstract
Localized 1H MRS in alert monkeys was performed in a vertical 7T/60cm MR system utilizing increased sensitivity and spectral dispersion gained at high field. Refinements of acquisition and correction strategies were necessary to minimize magnetic susceptibility artifacts induced by respiration and mouth or body movement. Periods with major motion-artifacts were rejected, while a frequency/phase correction was performed on the remaining single spectra before averaging. In resting periods, both spectral amplitude and linewidth, i.e. the voxel shim, were unaffected permitting reliable measurements. The corrected spectra afforded the reliable quantitative detection of 6 to 10 brain cerebral metabolites of 1-mL volumes.