In vivo CSI of glutamate in the monkey brain

Juchem, C; Merkle, H; Logothetis, NK; Pfeuffer, J

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In vivo CSI of glutamate in the monkey brain

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Juchem, C
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Logothetis, NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Pfeuffer, J
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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引用

Juchem, C., Merkle, H., Logothetis, N., & Pfeuffer, J. (2004). In vivo CSI of glutamate in the monkey brain. In 12th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2004) (pp. 8).

引用: https://hdl.handle.net/11858/00-001M-0000-0013-D959-5

要旨

CSI studies of metabolites in the human brain typically suffer from poor spatial resolution or they are restricted to substances with strong peaks that are visible at longer echo times. In this study, enhanced spectral dispersion and sensitivity at high field in combination with short echo times was utilized to measure a pure glutamate map in the ventricle region of the manlike monkey model (Macaca mulatta), instead of a sum of glutamate and glutamine. In addition, first CSI results in the occipital lobe are presented with a high spatial resolution in the millimeter range.