In vivo CSI of glutamate in Macaca mulatta brain

Juchem, C; Merkle, H; Logothetis, NK; Pfeuffer, J

doi:10.1007/s10334-003-0017-5

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In vivo CSI of glutamate in Macaca mulatta brain

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Juchem, C
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Logothetis, NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Pfeuffer, J
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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https://link.springer.com/content/pdf/10.1007/s10334-003-0017-5.pdf
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引用

Juchem, C., Merkle, H., Logothetis, N., & Pfeuffer, J. (2003). In vivo CSI of glutamate in Macaca mulatta brain. Poster presented at 20th Annual Scientific Meeting of the ESMRMB 2003, Rotterdam, Netherlands.

引用: https://hdl.handle.net/11858/00-001M-0000-0013-DBD8-8

要旨

Glutamate is the main excitatory neurotransmitter in the CNS and plays together with glutamine an important role in brain physiology. A quantitative spatially resolved analysis of glutamate separate from glutamine is therefore of particular neuroscientific interest. In a pilot 1H Chemical-Shift Imaging (CSI) study we demonstrate that maps of sufficiently high spectral and spatial resolution can be obtained to initially map areas of largely different glutamate concentration (e.g. neural tissue vs. ventricles).