Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS 
signalling

Zimmermann, Gunther; Papke, Björn; Ismail, Shehab; Vartak, Nachiket; Chandra, Anchal; Hoffmann, Maike; Hahn, Stephan A.; Triola, Gemma; Wittinghofer, Alfred; Bastiaens, Philippe I. H.; Waldmann, Herbert

doi:10.1038/nature12205

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Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling

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/persons/resource/persons118799

Zimmermann, Gunther
Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons118356

Papke, Björn
Abt. II: Systemische Zellbiologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons118803

Ismail, Shehab
Sonstige Wissenschaftliche Organisationseinheiten, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons118370

Vartak, Nachiket
Abt. II: Systemische Zellbiologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons118801

Chandra, Anchal
Abt. II: Systemische Zellbiologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons98731

Triola, Gemma
Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons98738

Wittinghofer, Alfred
Sonstige Wissenschaftliche Organisationseinheiten, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons98677

Bastiaens, Philippe I. H.
Abt. II: Systemische Zellbiologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons98735

Waldmann, Herbert
Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

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Zimmermann, G., Papke, B., Ismail, S., Vartak, N., Chandra, A., Hoffmann, M., et al. (2013). Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling. Nature, 497(7451): 1, pp. 638-642. doi:10.1038/nature12205.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0013-FD8E-2

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