English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Catalytic Asymmetric Intramolecular Michael Reaction of Aldehydes

MPS-Authors
/persons/resource/persons58610

Hechavarria Fonseca,  Maria Teresa
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58764

List,  Benjamin
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Ressource
No external resources are shared
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Hechavarria Fonseca, M. T., & List, B. (2004). Catalytic Asymmetric Intramolecular Michael Reaction of Aldehydes. Angewandte Chemie International Edition, 43(30), 3958-3960. doi:10.1002/anie.200460578.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0014-A4B4-2
Abstract
Efficient organocatalysis of the intramolecular Michael reaction of formyl enones, such as 1, by an imidazolidinone catalyst leads to the corresponding ketoaldehydes in excellent yields and with high enantioselectivities (see scheme). This reaction can be included as part of a tandem process, as the ketoaldehyde products undergo aldolization readily to give hydrindenones, such as 2. Bn=benzyl, Ms=methanesulfonyl.