English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Catalytic Asymmetric Protonation of Silyl Ketene Imines

MPS-Authors
/persons/resource/persons58593

Guin,  Joyram
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons59067

Varseev,  Georgy
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58764

List,  Benjamin
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Resource
No external resources are shared
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Guin, J., Varseev, G., & List, B. (2013). Catalytic Asymmetric Protonation of Silyl Ketene Imines. Journal of the American Chemical Society, 135(6), 2100-2103. doi:10.1021/ja312141b.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0014-A42B-9
Abstract
An efficient catalytic and highly enantioselective protonation of silyl ketene imines is described. The reaction is catalyzed by the chiral phosphoric acids TRIP or STRIP in the presence of a stoichiometric amount of methanol as the proton source and silyl acceptor. A variety of substituted racemic silyl ketene imines have been transformed into highly enantioenriched nitriles.