Stereoselective Synthesis of Dienyl-Carboxylate Building Blocks: Formal 
Synthesis of Inthomycin C

Souris, Caroline; Frébault, Frédéric; Patel, Ashay; Audisio, Davide; Houk, K. N.; Maulide, Nuno

doi:10.1021/ol401226y

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Stereoselective Synthesis of Dienyl-Carboxylate Building Blocks: Formal Synthesis of Inthomycin C

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Souris, Caroline
Research Group Maulide, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Frébault, Frédéric
Research Group Maulide, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Audisio, Davide
Research Group Maulide, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Maulide, Nuno
Research Group Maulide, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Citation

Souris, C., Frébault, F., Patel, A., Audisio, D., Houk, K. N., & Maulide, N. (2013). Stereoselective Synthesis of Dienyl-Carboxylate Building Blocks: Formal Synthesis of Inthomycin C. Organic Letters, 15(13), 3242-3245. doi:10.1021/ol401226y.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0014-A39A-6

Abstract

A direct synthesis of stereodefined halodienes is reported. Those key building blocks enable a concise access to polyenic products, as demonstrated in a modular synthesis of Inthomycin C.