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Synthesis of characteristic lipopeptides of lipid modified proteins employing the allyl ester as protecting group

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Waldmann,  Herbert
Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

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Citation

Schmittberger, T., Cotte, A., & Waldmann, H. (1998). Synthesis of characteristic lipopeptides of lipid modified proteins employing the allyl ester as protecting group. CHEMICAL COMMUNICATIONS, (8), 937-938. doi:10.1039/a708749g.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0014-71B2-A
Abstract
Lipidated peptides which represent characteristic lipid modified substructures of lipidated human G(alpha O) protein and the human N- and R-Ras proteins were built up efficiently by employing the selective Pd-0-mediated removal of allyl esters under very mild conditions as the key step.