ENZYMATIC PROTECTING GROUP TECHNIQUES IN BIOORGANIC SYNTHESIS

REIDEL, A; Waldmann, Herbert

doi:10.1002/prac.19933350202

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ENZYMATIC PROTECTING GROUP TECHNIQUES IN BIOORGANIC SYNTHESIS

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Waldmann, Herbert
Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

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REIDEL, A., & Waldmann, H. (1993). ENZYMATIC PROTECTING GROUP TECHNIQUES IN BIOORGANIC SYNTHESIS. JOURNAL FUR PRAKTISCHE CHEMIE-CHEMIKER-ZEITUNG, 335(2), 109-127. doi:10.1002/prac.19933350202.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0014-9C17-1

Abstract

The development and the application of enzyme-catalyzed transformations for the introduction and/or removal of protecting groups for hydroxyl-, amino-, mercapto- and carboxy functions is discussed. The various examples highlight the advantageous application of enzymes in comparison to classical chemical techniques in the chemistry of peptides, carbohydrates, alkaloids and steroids. Thus, the biocatalysts not only complement the arsenal of classical chemical methods, but offer viable and interesting alternatives to them.