English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Journal Article

Versatile Access to Chiral Indolines by Catalytic Asymmetric Fischer Indolization

MPS-Authors
/persons/resource/persons58800

Martínez,  Alberto
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons59096

Webber,  Matthew J.
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58836

Müller,  Steffen
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58764

List,  Benjamin
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Martínez, A., Webber, M. J., Müller, S., & List, B. (2013). Versatile Access to Chiral Indolines by Catalytic Asymmetric Fischer Indolization. Angewandte Chemie International Edition, 52(36), 9486-9490. doi:10.1002/anie.201301618.


Cite as: https://hdl.handle.net/11858/00-001M-0000-0014-C9F6-4
Abstract
“Fisching” for complexity: The chiral Brønsted acid (R)‐STRIP catalyzes the asymmetric Fischer indolization of a range of monosubstituted cyclopentanones and cyclohexanones to give chiral fused indolines bearing a quaternary stereogenic center at the 3‐position. The method has been extended to include substrates bearing a tethered nucleophile, thus allowing for enantioselective indolization/ring‐closing cascades to complex propellanes featuring two vicinal quaternary stereocenters.