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Zeitschriftenartikel

Uniform transitions of the general RNA polymerase II transcription complex.

MPG-Autoren
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Söding,  J.
Research Group of Computational Biology, MPI for Biophysical Chemistry, Max Planck Society;

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Cramer,  P.
Department of Molecular Biology, MPI for Biophysical Chemistry, Max Planck Society;

Volltexte (frei zugänglich)

1937955.pdf
(Verlagsversion), 2MB

Ergänzendes Material (frei zugänglich)

1937955-Suppl.pdf
(Ergänzendes Material), 6MB

Zitation

Mayer, A., Lidschreiber, M., Siebert, M., Leike, K., Söding, J., & Cramer, P. (2010). Uniform transitions of the general RNA polymerase II transcription complex. Nature Structural and Molecular Biology, 17(10), 1272-1278. doi:10.1038/nsmb.1903.


Zitierlink: http://hdl.handle.net/11858/00-001M-0000-0015-8216-5
Zusammenfassung
The genome-wide occupancy profiles for yeast RNA polymerase II in different phosphorylated forms, as well as transcription factors, are presented. The resulting analysis captures a 5' transition in which initiation factors are replaced by a general set of elongation factors that form a productive complex, which disassembles in two steps at the 3' end of the gene.