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Journal Article

Sugarcoating ER Stress

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Vincenz,  Lisa
Hartl, Franz-Ulrich / Cellular Biochemistry, Max Planck Institute of Biochemistry, Max Planck Society;

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Hartl,  F. Ulrich
Hartl, Franz-Ulrich / Cellular Biochemistry, Max Planck Institute of Biochemistry, Max Planck Society;

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Citation

Vincenz, L., & Hartl, F. U. (2014). Sugarcoating ER Stress. CELL, 156(6), 1125-1127. doi:10.1016/j.cell.2014.02.035.


Cite as: https://hdl.handle.net/11858/00-001M-0000-0019-0D33-C
Abstract
The hexosamine biosynthetic pathway (HBP) generates metabolites for protein N-and O-glycosylation. Wang et al. and Denzel et al. report a hitherto unknown link between the HBP and stress in the endoplasmic reticulum. These studies establish the HBP as a critical component of the cellular machinery of protein homeostasis.