Long noncoding RNAs usher in a new era in the biology of enhancers

Ørom, Ulf Andersson; Shiekhattar, Ramin

doi:10.1016/j.cell.2013.08.028

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Long noncoding RNAs usher in a new era in the biology of enhancers

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Ørom, Ulf Andersson
Long non-coding RNA (Ulf Andersson Ørom), Independent Junior Research Groups (OWL), Max Planck Institute for Molecular Genetics, Max Planck Society;

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Ørom, U. A., & Shiekhattar, R. (2013). Long noncoding RNAs usher in a new era in the biology of enhancers. Cell, 154(6), 1190-1193. doi:10.1016/j.cell.2013.08.028.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0019-10CF-8

Abstract

Enhancer-associated long noncoding RNAs act over long distances and across chromosomes to activate transcription at distal promoters. Here, we address the latest advances made toward understanding the role of long noncoding RNA expression and the involvement of these RNAs in enhancer function through association with protein factors and modulation of chromatin structure.