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Journal Article

Interactions between endocrine and circadian systems.

MPS-Authors
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Tsang,  A. H.
Research Group of Circadian Rhythms, MPI for biophysical chemistry, Max Planck Society;

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Barclay,  J. L.
Research Group of Circadian Rhythms, MPI for biophysical chemistry, Max Planck Society;

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Oster,  H.
Research Group of Circadian Rhythms, MPI for biophysical chemistry, Max Planck Society;

Fulltext (public)

2028123.pdf
(Publisher version), 407KB

Supplementary Material (public)
There is no public supplementary material available
Citation

Tsang, A. H., Barclay, J. L., & Oster, H. (2014). Interactions between endocrine and circadian systems. Journal of Molecular Endocrinology, 52(1), R1-R16. doi:10.1530/JME-13-0118.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0019-7A68-4
Abstract
In most species, endogenous circadian clocks regulate 24-h rhythms of behavior and physiology. Clock disruption has been associated with decreased cognitive performance and increased propensity to develop obesity, diabetes, and cancer. Many hormonal factors show robust diurnal secretion rhythms, some of which are involved in mediating clock output from the brain to peripheral tissues. In this review, we describe the mechanisms of clock-hormone interaction in mammals, the contribution of different tissue oscillators to hormonal regulation, and how changes in circadian timing impinge on endocrine signalling and downstream processes. We further summarize recent findings suggesting that hormonal signals may feed back on circadian regulation and how this crosstalk interferes with physiological and metabolic homeostasis.