Structure Guided Design and Kinetic Analysis of Highly Potent Benzimidazole 
Inhibitors Targeting the PDEδ Prenyl Binding Site

Zimmermann, Gunther; Schultz-Fademrecht, Carsten; Küchler, Philipp; Murarka, Sandip; Ismail, Shehab; Triola, Gemma; Nussbaumer, Peter; Wittinghofer, Alfred; Waldmann, Herbert

doi:10.1021/jm500632s

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Structure Guided Design and Kinetic Analysis of Highly Potent Benzimidazole Inhibitors Targeting the PDEδ Prenyl Binding Site

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Zimmermann, Gunther
Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons128661

Küchler, Philipp
Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons118542

Murarka, Sandip
Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons118803

Ismail, Shehab
Sonstige Wissenschaftliche Organisationseinheiten, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons98731

Triola, Gemma
Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons98738

Wittinghofer, Alfred
Sonstige Wissenschaftliche Organisationseinheiten, Max Planck Institute of Molecular Physiology, Max Planck Society;

/persons/resource/persons98735

Waldmann, Herbert
Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society;

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Zimmermann, G., Schultz-Fademrecht, C., Küchler, P., Murarka, S., Ismail, S., Triola, G., et al. (2014). Structure Guided Design and Kinetic Analysis of Highly Potent Benzimidazole Inhibitors Targeting the PDEδ Prenyl Binding Site. Journal of Medicinal Chemistry, 57(12), 5435-5448. doi:10.1021/jm500632s.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0019-BA15-7

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